I am assuming this to be SQLCommand and SQLCommand Builder:
The SQLCommand Object is used to executes SQL statements and Stored Procedures against the data source. It execute all kind of SQL queries like Insert, update etc.
SqlCommand cmd = new SqlCommand("your sql statements", Connection);
The SqlCommandBuilder can be used to build and execute SQL queries based on the select command that you will supply. It provides the feature of reflecting the changes made to a DataSet or an instance of the SQL server data. The CommandBuilder opens the Connection associated with the DataAdapter Object and makes a round trip to the server each and every time and it's asked to construct the action queries.
The SqlCommandBuilder object acts as a listener for RowUpdating events, whenever the DataAdapter property is set. You can create a SqlCommandBuilder object to automatically generate SQL statements for single table updates if you set the SelectCommand property of the SqlDataAdapter.
SqlDataAdapter adapter = new SqlDataAdapter("your sql statement", connection);
SqlCommandBuilder cmdBuilder = new SqlCommandBuilder(adapter);
//Here you can do any modification to the selected data
ds.Tables.Rows[i].ItemArray = Convert.ToInt32 (ds.Tables.Rows[i].ItemArray) + 100;
//Here save the data to the datasource
The above code select data from database and update it with the help of SqlCommandBuilder object and saves back to the datasource.